Comparing free water imaging and magnetization transfer measurements in schizophrenia

Comparing free water imaging and magnetization transfer measurements in schizophrenia.

Diffusion weighted imaging (DWI) has been extensively used to study the microarchitecture of white matter in schizophrenia. However, popular DWI-derived measures such as fractional anisotropy (FA) may be sensitive to many types of pathologies, and thus the interpretation of reported differences in these measures remains difficult. Combining DWI with magnetization transfer ratio (MTR) - a putati...

Pathological Assessment of Brain White Matter in Relapsing-Remitting MS Patients using Quantitative Magnetization Transfer Imaging

Introduction: Multiple sclerosis (MS) is characterized by lesions in the white matter (WM) of the central nervous system. Magnetic resonance imaging is the most specific and sensitive method for diagnosis of multiple sclerosis. However, the ability of conventional MRI to show histopathologic heterogeneity of MS lesions is insufficient. Quantitative magnetization transfer imaging (qMTI) is a rel...

Gray and white matter brain abnormalities in first-episode schizophrenia inferred from magnetization transfer imaging.

BACKGROUND Neuroimaging studies suggest that schizophrenia is associated with gray and possibly white matter changes. It is unclear whether these changes are present at illness onset or which brain structures are selectively affected. New imaging methods such as magnetization transfer imaging may be more sensitive than conventional volumetric imaging to the subtle structural brain changes in sc...

Quantitative Magnetization Transfer Imaging Techniques and Applications

Magnetization Transfer in Cardiac Truefisp Imaging

Session IX: Friday, February 2, 2007 307. MAGNETIZATION TRANSFER IN CARDIAC TRUEFISP IMAGING Oliver M. Weber, PhD, Klaus Scheffler, PhD, Oliver Bieri, PhD. University of Basel, Switzerland, Basel, Switzerland. Introduction: Recently, we showed that the rapid succession of high flip angle RF pulses in conventional balanced steady state free precession (bSSFP) sequences causes an on-resonancemagn...